It is tough to remove Radiesse once it is injected and it lasts anywhere from ten months to a year. Hyaluronic acid fillers are the only ones that can be dissolved because hyaluronic acid appears naturally in your body.
This is not recommended, as there are better treatment options to suit your request. The molecules in Radiesse are too large for the lips and may offer lumpy, undesirable results. I suggest you look into other hyaluronic acid products like Restylane or Juvederm. Many of my patients love Juvederm because it gives their lips a soft, luscious plump.